Pfizer or Astra Zen...
 

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[Closed] Pfizer or Astra Zeneca vaccine ?

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 diz
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If given the choice of the 2 vaccines which would people take and why?

 
Posted : 01/01/2021 6:10 pm
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Would you refuse one or the other?

Do you know which manufacturer of flu jab you get? Who makes your cancer drugs?

We are all desperate for knowledge but I think we are all trying to be too clever here.

 
Posted : 01/01/2021 6:15 pm
 db
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I think the BioNTech, Fosun Pharma, Pfizer vaccine. The RNA type seems logical to me.
https://en.m.wikipedia.org/wiki/RNA_vaccine

However I will take whatever I’m offered!

 
Posted : 01/01/2021 6:17 pm
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It’s not the Matrix! I doubt we’ll even have a choice 😉
I’ll take the one that’s available soonest please.

 
Posted : 01/01/2021 6:18 pm
 db
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Oh and more info here if people want to read about it;

https://www.who.int/emergencies/diseases/novel-coronavirus-2019/covid-19-vaccines

 
Posted : 01/01/2021 6:18 pm
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If given the choice

I doubt you will get this.

Had a eye rolling discussion with someone not wanting to have as they didn't know possible side effects. I asked them what the side effects of paracetamol and ibuprofen were, they didn't know but declared them both safe as you can buy them without prescription. Ho hum..

 
Posted : 01/01/2021 6:21 pm
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Not commenting on the vaccines as not allowed (work for az).
But paracetamol would likely not be approved now if it was asked as its toxicity would be too high for non prescription medicines

 
Posted : 01/01/2021 6:25 pm
 pk13
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Not fussed just bang it in my arm please.

 
Posted : 01/01/2021 6:28 pm
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I doubt anyone will get a choice TBH. Maybe if you paid privately at a clinic. Any kind of state organised vaccination program will just have what’s available in that area.

FWIW I’ll have the vaccination as soon as it’s offered.

 
Posted : 01/01/2021 6:32 pm
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@grahamt1980, AZ or P? No comments needed... 😉

 
Posted : 01/01/2021 6:36 pm
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AZ for me. Pfizer have a history of making medicines with unexpected side effects that are hard to deal with.

 
Posted : 01/01/2021 6:41 pm
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AZ for me. Pfizer have a history of making medicines with unexpected side effects that are hard to deal with.

I'm not going to rise to that.

 
Posted : 01/01/2021 6:45 pm
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Even answering that would be enough. At the moment I would have whichever one is going to get to me first.
After that. . . . Will see

 
Posted : 01/01/2021 6:57 pm
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AZ for you as well then mefty, to be on the safe side 😀

 
Posted : 01/01/2021 6:57 pm
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Both, one in each arm. Then down the pub.

 
Posted : 01/01/2021 7:25 pm
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Posted : 01/01/2021 7:39 pm
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If given the choice, the AZ vaccine because it's manufactured in the UK so has lower vaccine miles 😉

 
Posted : 01/01/2021 7:47 pm
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There won’t be any choice. However look at the details

Pfizer has to be kept in a very cold fridge, Oxford does not. Now that’s not to say they can’t defrost it etc, but which centres have been set up first, and which have the cold fridges, or more relevant likely not to.

Isn’t one 90% effective, the other 70%?

 
Posted : 01/01/2021 7:47 pm
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Had the pfizer last week. Noticed no side effects other than a slightly sore arm.

 
Posted : 01/01/2021 7:49 pm
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Whatever I'm given will do. The calculator predicted I would be getting the jabs in October/November, which seems a little slow.

Edit I'm 58 with no real underlying health issues.

 
Posted : 01/01/2021 7:51 pm
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Isn’t one 90% effective, the other 70%?

Assuming they inhibit transmission by the same percentage it's kinda moot, simplistically modeled as everyone getting the vaccine on the same day, then after a couple of weeks you reach an infection rate so low as to be effectively zero anyway (4 days from exposure to symptoms at which point you should isolate, so an average of 2 days), so if everyone had the 70% vaccine and the number remained ~1.2 thats (0.3*1.2)^7, the infection rate drops to 0.08% of what it would have been.

The flipside is, no one knows how effective they are at preventing transmission, the data doesn't exist yet (assuming they're comparable seems reasonable on the assumption that to be effective they result in a very low viral load).

 
Posted : 01/01/2021 8:13 pm
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I'll go for the AZ vaccine if I have the choice. 2nd choice the Russian Sputnik 🤔😉

 
Posted : 01/01/2021 8:17 pm
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You’d be utterly insane to not go with Astra Zeneca

No this has nothing to do with any shares we may have with AZ

 
Posted : 01/01/2021 8:19 pm
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What ever I am offered.

Then prahaps the other one as well.

 
Posted : 01/01/2021 8:21 pm
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Isn’t one 90% effective, the other 70%?

Haven't bothered my arse looking for publications but I **THINK** that outcomes were a bit different too:
Tha AZ study(ies) gave all participants a set of full-on testing kits (deep-throat/up the nose & scrape the back of yr pituitary) to use every week. I believe that the Pfizer study waited for subjects to show symptoms before testing them.

If that's right, then Pfizer was 90ish% effective at preventng symptomatic infection, while AZ was 62-90% effective at preventing detectable infection.

[are the studies published now - do we have ^ that info?]

[[seems we sort of do. Pfizer study:
Confirmed COVID-19 was defined as having a positive RT-PCR respiratory specimen for SARS-CoV-2 AND at least one of the following: fever, new or increased cough, new or increased shortness of breath, chills, new or increased muscle pain, new loss of taste or smell, sore throat, diarrhea, or vomiting.]]

 
Posted : 01/01/2021 8:23 pm
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The most effective medicine is the one that the patient is happy to take...
As long as enough people get vaccinated it won’t matter which one they have...
Worrying about 62 vs 95% trial results is kinda pointless. They are both effective.
Doi- volunteered in the Oxford trial. Weekly swabs continuing...

 
Posted : 01/01/2021 8:29 pm
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Just reading that they will try and match for second dose but can mix if necessary. So I think you will just be asked to line up and take what’s on offer.

 
Posted : 01/01/2021 8:33 pm
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Ideally I’ll have one that doesn’t contain part of the disease as being immune suppressed I would worry and I think they will too. I’ve not looked if either contain a live dose as I trust specialists and NHS to tell me which is safe for me. According to the calculator it’ll be March time.

 
Posted : 01/01/2021 9:20 pm
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The only person I know personally who actually knows this science rather than being an internet armchair expert says she'd prefer the oxford if given a choice, which is good enough for me.

I'll happily have whatever offered. And the sooner the better - only because if I get mine soon as a 10th priority (lowest) it means all those I love and care for more vulnerable than me will have got it even sooner.

 
Posted : 01/01/2021 9:29 pm
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Which one has the best 5G reception? I'll take that one.

 
Posted : 01/01/2021 9:29 pm
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Given the organisational abilities of my GP surgery, I’ll be lucky if I get the TB one.

 
Posted : 01/01/2021 9:40 pm
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If approved in time (March / April) I can see most getting the Janssen vaccine as single dose and can be stored at fridge temperature.

 
Posted : 01/01/2021 9:42 pm
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I'll take whichever one is being offered. As the Omni calculator thinks I won't get vaccinated until Dec 21/Jan 22 I'm not too worried about unknown side effects.

 
Posted : 01/01/2021 9:48 pm
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I'm up for any of the mRNA vaccines, just because I think the mechanism is cool.

The mechanism for other vaccines is also pretty cool though so I guess it's win-win.

 
Posted : 01/01/2021 10:39 pm
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Well, I’ve had the Pfizer one and haven’t grown anything extra, other than extreme grumpiness and an overwhelming intolerance for Covid conspiracy theories (unrelated to this thread btw!)

I guess my answer would be the Pfizer
One then?

 
Posted : 01/01/2021 11:10 pm
 poah
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Ideally I’ll have one that doesn’t contain part of the disease

not going to give you any immunity to it then lol

just because I think the mechanism is cool.

Makes a mockery of the Eukaryotic translation pathway 😛

 
Posted : 02/01/2021 1:12 am
 hugo
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Isn’t one 90% effective, the other 70%?

An oversimplification but a good point.

Would you refuse one or the other?

No, but that's moving the goalposts. The question is which one would you choose?

My answer would be either but would have a preference for the Pfizer one as it's been proved to have a higher efficacy. They have both be proven safe.

This doesn't have to be confrontational or polarising. It's a reasonable question.

 
Posted : 02/01/2021 4:32 am
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Ideally I’ll have one that doesn’t contain part of the disease as being immune suppressed I would worry and I think they will too.

Question.

Do not all vaccines work by imitating in one way or another the thing itself you are vaccinating against?

 
Posted : 02/01/2021 6:38 am
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Is there any truth in this from the New York Times that Britain is adopting a mix and match approach? I can't believe they would? Surely some sort of clinical trial is required? Scary that they are saying 'if the first vaccine is unknown' This should never be the case surely?

Mix and match vaccine

 
Posted : 02/01/2021 12:24 pm
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Seems just like something our fearless leaders would do (along with changing from 3 to 12 weeks between doses, to enable more people to get at least one jab...)

 
Posted : 02/01/2021 12:36 pm
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I imagine our world getting vaccination task force can’t actually keep tabs on who it has jabbed with what.

 
Posted : 02/01/2021 1:25 pm
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The the nytimes article, read the response I posted to it the first time someone posted it a bit up the thread...

 
Posted : 02/01/2021 1:56 pm
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THE FOUR MAIN TYPES OF COVID-19 VACCINE
There are four categories of vaccines in clinical trials: WHOLE VIRUS, PROTEIN SUBUNIT, VIRAL VECTOR and NUCLEIC ACID (RNA AND DNA). Some of them try to smuggle the antigen into the body, others use the body’s own cells to make the viral antigen.

Whole Virus = "both types use well-established technology and pathways for regulatory approval, but live attenuated ones may risk causing disease in people with weak immune systems"

 
Posted : 02/01/2021 4:53 pm
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Whichever is closest frankly, although it’ll be months and months before I’ll be offered one.

My wife was supposed to have her Pfizer one weeks ago, but we were in Wales and we have a seemingly laissez-faire attitude to rolling it out it’s been pushed back a couple of times.

On the plus side, we’ve had 150k confirmed cases in Wales, if for every confirmed cases there are 9 non-confirmed so it’s not a bad guess that 1.5 million people in Wales have had COVID, that’s about half the population, it’s also rising at 2k-3k confirmed cases a day, so that’s 20k ‘real’ cases, in a mere 75 days everyone in Wales would have had it at least once.

 
Posted : 02/01/2021 8:34 pm
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Having the second dose in 12 weeks has a sound basis, the messaging has just been handled abysmally by Govt/PHE/NHSE as usual. The first dose in the Oxford trials gives around 50% immunity but 90% reduction in severe disease. Scaled up to and more of a population this has a significant impact on disease severity and the burden in hospitals (which obviously have to treat a lot of other conditions from which people die). I’m booked to get the Pfizer jab next week and happy to wait a longer for the second jab and do my bit.

 
Posted : 02/01/2021 9:09 pm
 diz
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Ended up having the Pfizer vaccine last night, second dose due on Good Friday. Although a choice was promised, it never materialised. However I had decided I was going to have the Pfizer due to it being the most effective (allegedly). I've got a little bit of a aching arm this morning but that's all.

 
Posted : 08/01/2021 9:50 am
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When I got my flu jab in December, the nurse said patient's had been asking 'what's in it'. I joked that I wouldn't mind a 5G chip then could make calls on my hand and not use my phone !!

Some right nutters out there. Any will do for me, the sooner we get back to 'new normal' the better. My wife might get to hug her mum !

 
Posted : 08/01/2021 10:31 am
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I'm not convinced the healthy under 50s population will get either vaccine this year. By the time the vulnerable categories have had their second doses we will be well into the summer and stockpiling any further doses for the next winter.

 
Posted : 08/01/2021 10:55 am
 Drac
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I imagine our world getting vaccination task force can’t actually keep tabs on who it has jabbed with what.

Just like all medications and vaccines prescribed by your GP funnily enough they are.

I got my Pfizer one yesterday slightly sore arm last night but that’s it.

 
Posted : 08/01/2021 10:58 am
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Am I right in thinking that GPs IT is standalone rather than country wide? Normally your doc has all your records. How will it work when we have roving teams and mega centres?

I have trust in the NHS, but not the so called Task force led by Zahawi and Bingham.

 
Posted : 08/01/2021 2:40 pm
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vaccination task force can’t actually keep tabs on who it has jabbed with what.

Wife got a nice little credit card sized bit of card with her Pfizer vaccine details on and was told not to lose it. Promptly put it on the dashboard of the car and now it's safely stored somewhere down the back of it 🙁

 
Posted : 08/01/2021 3:15 pm
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There was a doctor on TV last night, apparently he'd had several people (assuming elderly or high risk of covid complications, possibly both) turning up for a vaccine jab and asking which one it would be? When told it was the Pfizer/BioNtech version they refused the jab as it is made in Germany/Belgium and would only come back when the English vaccine was available. No question about rushed development or lack of testing, or even crazy mind controlling 5g microchips, but no chance they're going to have a vaccine that isn't made in the UK. The mind boggles at the stupidity of some people

 
Posted : 08/01/2021 3:16 pm
 irc
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Am I right in thinking that GPs IT is standalone rather than country wide?

In Scotland anyway the systems the GP practices use talk to other systems. For example When GPs working for the Out of Hours Service get a call sent to the laptop in the car there is amongst other info a list of medicines prescribed for that patient by their GP.

AS I don't use them I can't tell you all the info on them but I would be amazed if something like Covid vaccination wasn't on a national database as well. When I got my jag yesterday the nurse doing it looked me up on a tablet and had my medical record there. Thi

I got the Pfizer. Slight tenderness in the arm otherwise nothing so far for side effects.

 
Posted : 08/01/2021 3:32 pm
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Hopefully my cynicism is misplaced.

 
Posted : 08/01/2021 3:35 pm
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The moderna one received approval today (10m doses ordered) with the single shot J&J vaccine like to be approved in 5 weeks.

I think that gives the U.K. around 130m doses by the end of June.

A quick scan of the European broadsheets suggests that leaders in Germany, France, Italy, Spain and Netherlands are all getting slated for their perceived failings with vaccine rollout - which would suggest it’s harder to get right than the armchair critics would have us believe.

 
Posted : 08/01/2021 3:36 pm
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Am I right in thinking that GPs IT is standalone rather than country wide? Normally your doc has all your records. How will it work when we have roving teams and mega centres?

It's going fine. There's not much point giving more detail, but the vaccination records being input are flowing through to the GP systems.

And then into my reports 🙂

 
Posted : 08/01/2021 6:28 pm
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Thanks Rob - good to know.

 
Posted : 08/01/2021 6:45 pm
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When told it was the Pfizer/BioNtech version they refused the jab as it is made in Germany/Belgium and would only come back when the English vaccine was available.

I read that as well. My instance reaction was ' well they should be put right at back of queue then, and if they die between now and then, xxxx em'

Harsh perhaps, but we shouldn't be pandering to the views of some old ignorant racists, whilst the rest of the country bends over backwards to keep them safe

 
Posted : 08/01/2021 7:20 pm
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I’m not convinced the healthy under 50s population will get either vaccine this year. By the time the vulnerable categories have had their second doses we will be well into the summer and stockpiling any further doses for the next winter.

I'm not convinced they should either, it should go to the developing worlds vulnerable.

 
Posted : 08/01/2021 7:20 pm
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An expecting that business travel anywhere will require a vaccine though.
So there will be an amount of under 50's vaccinated

 
Posted : 08/01/2021 7:45 pm
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An expecting that business travel anywhere will require a vaccine though.
So there will be an amount of under 50’s vaccinated

Given you can't really distinguish between business and leisure travel, that boils down to all travel requiring a vaccine, and that in turn boils down to sufficient vaccine being available for people to be able to privately pay for it. I don't doubt that Musk and Bezos can get the vaccine immediately if they want it, but for normal people?

 
Posted : 08/01/2021 8:13 pm
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Agreed, I have no idea how it would be regulated for most.

 
Posted : 08/01/2021 8:35 pm
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Considering at the moment there is no plan to vaccinate pilots & cabin crew, nobody will be going very far anyway!

What kind of vaccine is the single shot J&J?

 
Posted : 08/01/2021 8:41 pm
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Scotland have committed to vaccinating all adults. The only 2 folks I personally know whom have had covid have bother really suffered, one 3 months to get back to semi normal, 1 still off work. Both no underlying conditions.

I'm apparently at greater risk due to my asthma, but not sure if I'll even be included in a priority group. So I'm pretty keen to get a dose at some point with rest of the under 50s, as at 44 with asthma, it's definitely not a virus I want to pick up.

 
Posted : 08/01/2021 8:43 pm
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tpbiker

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When told it was the Pfizer/BioNtech version they refused the jab as it is made in Germany/Belgium and would only come back when the English vaccine was available.

I read that as well. My instance reaction was ‘ well they should be put right at back of queue then, and if they die between now and then, xxxx em’

Harsh perhaps, but we shouldn’t be pandering to the views of some old ignorant racists, whilst the rest of the country bends over backwards to keep them safe

Not harsh at all. My reaction, if the story is true, was a lot more severe.

 
Posted : 08/01/2021 8:48 pm
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'Dr William Welfare, Covid-19 response director at PHE', I'll have whatever this bloke's armed with.

 
Posted : 08/01/2021 9:32 pm
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I would have the pfizer one as I live in a city and thus leaving the easier to store one for those in rural areas

 
Posted : 08/01/2021 9:46 pm
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In Scotland anyway the systems the GP practices use talk to other systems.

Not very well. gp systems do not talk to hospital systems. You do get a key information summary but not the full recordsd. Its OK but not what it should be. some stuff is still sent by snail mail and then manually inputted I think

Why GPs do not have TRAK I do not know

 
Posted : 08/01/2021 9:51 pm
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Johnson has promised all english care home residents will have it by the end of the month. anyone want to bet on this? My guess is 70%

 
Posted : 08/01/2021 9:53 pm
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I am also in the Pfizer ‘MRNA is cool’ club. But frankly any. And soon.

I’m not at risk (48 and fit) but my dad died over Christmas and I want to be able to see my mum and my brother and sister and have a memorial service in Germany for him.

There’s no way I would travel at the moment because it is just not right to. But, despite telling myself that everyone is in the same boat - and indeed that he couldn’t be there for his mum or attend her funeral 40 years ago because of being on the other side of the Iron Curtain, it’s still very hard.

 
Posted : 08/01/2021 9:57 pm
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I want the newest one with the new quad-core microchip instead of the outdated pentium core 2 duo in the first vaccine.

 
Posted : 08/01/2021 9:59 pm
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My guess is 70%

In the words of Top Gear. Ambitious, but rubbish.

I'd say lucky to reach 50%.

 
Posted : 08/01/2021 10:01 pm
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My Mum's vaccination is definitely in her GPs records, and although it was given in a vaccination centre the nurse who did it was from her own surgery 25 miles away.

 
Posted : 08/01/2021 10:05 pm
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Sorry to hear about your Dad clover.

Re the computer systems, we're having to use two different systems that GPs don't normally use to both book patients and record the details of vaccines. The information does flow back to GP systems but the transfer isn't reliable presently, but at least it'll be in one place. In England (depending on sharing agreements), Trusts can access records for local patients normally (so a Manchester hospital can see a Manchester GPs patient data, for example) although it varies widely.

 
Posted : 08/01/2021 10:06 pm

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