Can anyone explain ...
 

  You don't need to be an 'investor' to invest in Singletrack: 6 days left: 95% of target - Find out more

[Closed] Can anyone explain Odds Ratios to me?

8 Posts
6 Users
0 Reactions
88 Views
Posts: 0
Free Member
Topic starter
 

How do you interpret odd ratios? Bigger number = higher chances of there being a relationship between the two things?

Say you had an odds ratio of 72.08 with 95%CI of 8.88-584.77 with a p-value of <0.001.

What's that in plain english?


 
Posted : 01/12/2012 1:36 pm
Posts: 8612
Full Member
 

Odds ratio is the chance of something happening in the study group vs. control, ie: odds ratio of 2 means the event is twice as likely in the study group as control, and 0.5 is the reverse. Doesn't reflect the chance of there being a relationship.

[i]Edit - what I've described appears to be the Relative Risk. OR is the ratio of an event happening to an event not happening for a given population[/i]

p value reflects the chance that the statistical difference between study and control groups is due to chance. By convention p<0.05 is regarded as good enough.

That 95% CI is enormous.

What's the context behind this?

Andy


 
Posted : 01/12/2012 1:41 pm
Posts: 6130
Full Member
Posts: 0
Free Member
Topic starter
 

Risk of symptomatic knee osteoarthritis as conferred by the presence of coexisting depressive disorders.


 
Posted : 01/12/2012 1:43 pm
Posts: 5559
Free Member
 

Odds ratio - what he said -odds of it in one goup compared to another group
CI - No idea
P value is effectively the odds of it being due to chance with the lower the number the less likely it is chance and 0.05 [ or 0.01being the point of "proof"


 
Posted : 01/12/2012 1:54 pm
Posts: 0
Free Member
Topic starter
 

So what they're saying is that if you have depression you're 78 times more likely to have symptomatic osteoarthritis of the knee than if you dont have depression? And that they're 95% confident that the odds are somewhere between 8.88 and 584.77, and they're virtually certain it's not down to chance.

That cant be correct can it?


 
Posted : 01/12/2012 2:50 pm
 RicB
Posts: 1518
Free Member
 

This page explains it well

[url] http://stats.org/stories/2008/odds_ratios_april4_2008.html [/url]

Essentially an odds ratio is the probability of something happening vs the probability of it not happening

Relative risk is the risk of one thing happening vs another thing

Either way whatever study you're reading sounds wrong! CI that wide either mean tiny sample size (unlikely with that p value), or a badly designed study


 
Posted : 01/12/2012 4:40 pm
Posts: 12
Free Member
 

What practical application is the answer going to have for you?

Step away from the keyboard. Maybe go out for a beer.


 
Posted : 01/12/2012 4:46 pm
 RicB
Posts: 1518
Free Member
 

Actually having re-read that link I think I'm wrong. I described Odds, not Odds Ratio


 
Posted : 01/12/2012 4:55 pm

6 DAYS LEFT
We are currently at 95% of our target!