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Apologies, a well posted about comment, though a unique question maybe. I have an existing bathroom with en-suite being built next door. It was an external cavity wall being reduced to single skin brick, to ceiling height. I say ceiling height as the existing bathroom has loft above (with in-line fan, via tile vent) and the new en-suite has a vaulted ceiling. And hereth doth the question lay. Hopefully the pic works.
With no space for an in-line fan in the new space, I have two options a) to have a further inline fan located in the existing loft space, but pulling air from the wall of the vaulted ceiling, above standard ceiling height. This option means it will be drawing air from the wall opposite where the shower will be, hardly premium, but the room isn’t huge. Or b) a wall mounted fan next to the shower with something like a humidistat and a constantly running feature/with boost perhaps.
Any thoughts on either option? Would both work perhaps or potentially work against each other? A or B? Or potentially both? TIA!

I would always go for an inline fan if possible. The normal advice is to site as high as possible, and as far as possible from where the fresh air is coming in (ie the door).
In your case, that would be 'A'.
PS Is that a completely new internal wall with the door on it? Go for a pocket sliding door, thank me later.
A
Keep it simple, are you allowed to connect the two into one roof vent? Even simpler
Of the two options, A seems better as an inline fan is always better. One other thing to consider is any steam will head up to and collect at the vaulted ceiling/wall junction so the ideal place for a fan is as high as possible in that area if at all possible
Thanks for all this. Much appreciated - especially comments re height. Noted! That was the plan with the inline, two fans venting into a ‘Y’ joint into the existing tile vent. Different heights could impact that I guess!
Yes - builder has a request in to quote for pocket door. Nothing internal built yet! Like all these things, we’ve gone over budget on 99% of the stuff so far!
Going nuclear on the extraction as we’ve done wet, damp bathrooms before!
Make the ducting as short, straight, smooth and large and insulated as possible. We have the 6" inline Manrose fans in ours with insulated ducting and steam in the bathroom is non-existent.
Fans? Plural?
That’s my aim. Do you use condensation traps or does the insulation do away the need?
Multiple rooms, one fan per. Didn’t use condensation traps as our ducting is rigid after the fan and makes its way outside before condensation it appears. In fact, during the recent cold snap there was a rather impressive icicle hanging off the vent grille.
High five for the icicle!! Cheers!
My goto is a fan with built in humidistat, rather than traditional timer or even occupancy sensor. The humidity level is adjustable and you know the fan will run as long as it needs rather than an arbitary 5 mins anybody uses the room. Might be a bit more expensive but worth it IMHO. https://www.tlc-direct.co.uk/Products/SLS100CHZ.html?source=msn&source=msn&campaign=shopping&ad_id=8894309929&kw=&network=o&matchtype=e&product_id=SLS100CHZ&product_partition_id=pla-1100603701294:aud-805618563&test=finalurl&msclkid=de8b215eff8b15e171b546cd28db85e7
Thanks for all this. Does anyone have an opinion on the two fan thing?
Something like dead slow suggests at B and an in-line over in the A spot?
I think you’re overthinking it, The en-suite in my place has a vaulted ceiling with a Velux window and never steams up nor grows mould, and the crap wall-mounted fan barely runs. Just crack the window open and all’s good. Two fans? Unless you want to evaluate your aerodynamics in your own wind tunnel it seems overkill.
The AC in the attached bedroom rarely pulls any moisture out of the air and it never goes above 55% relative humidity in there.
Does anyone have an opinion on the two fan thing?
Something like dead slow suggests at B and an in-line over in the A spot?
My view would be you'd be creating a lot of extra faff and expense for quite possible no extra benefit. At the end of the day you're trying to promote airflow in through the door and out through a vent or window, whether an extra fan would help or even hinder this, no idea.
As long as your room is properly insulated to minimise cold surfaces for condensation/mould growth, and you have a vent in a logical place to catch warm, wet air where it arrives and run long enough to expel most of it, you probably won't have a problem.
Humidity controlled variable speed constant extract is the best option as intermittent fans never get run for long enough. Smooth rigid insulated ducting, no flexy duct. Zehnder cv2 is decent. They also do a MeV whole house remote fan version.