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https://www.theatlantic.com/science/archive/2018/02/biohacking-stunts-crispr/553511/
So bloke claims to be able to modify someones dna to promote muscle growth. Injects himself with it. Then has kid and wonders if he may have made a mistake.
Two things;
1) There's clearly no test for this in sports medicine so it's undetectable doping unless they start doing DNA testing to look for changes.
2) What sort of ****er changes his dna and then fathers a child - **** knows what sort of inherited issues the child may have.
So, how long before the first DNA altered athlete wins a major event (or have they already)?
He's clearly an idiot but he won't have achieved any real level of DNA change, and certainly not in his son.
Injecting a single shot of CRISPR reagents into one muscle might have made very limited DNA changes in the area where he's injected it, but I doubt very much that he has the knowledge or ability to change enough control mechanisms to increase whole muscle strength to any great extent. The CRISPR won't have got any further than that, certainly not as far as his gametes. If he'd managed that then he'd be really in the clarts as altering germ cells by genetic engineering is against all international law, for obvious reasons.
Altering a grown adult to increase athletic ability via DNA changes isn't a goer with current technology as doing it n the right places (or whole-body) isn't possible.
Designer babies of this type have, however, been technically possible for 15-20 years so the idea of increasing potential athletic ability has been around for a long time. It's a lot more difficult than it looks at first glance though!
But yes, it was a mistake as a) it gives proper scientists a bad name, and b) makes other amateurs think they might be able to achieve a desired result and have a go themselves. They could inject any old crap!
Possibly attempting Myostatin mutation to increase muscle hypertrophy.
Flex Wheeler was one of a few BBers that naturally had the mutation.
He’s clearly an idiot but he won’t have achieved any real level of DNA change, and certainly not in his son.
Injecting a single shot of CRISPR reagents into one muscle might have made very limited DNA changes in the area where he’s injected it, but I doubt very much that he has the knowledge or ability to change enough control mechanisms to increase whole muscle strength to any great extent.
By the sound of him, he already has one arm significantly bigger than the other, so hopefully he's just trying to even things up.
I blame Barry marshal
Plenty of genetically modified humans out there. Some of them are even carrying non-hunan DNA!!!
Now for the science bit... CAR-T therapy takes immune cells, programs them to go after nasties with a non human piece of DNA (the C means chimeric), and these cells are put back into the patient. Not germline modification, but chimeras nevertheless. Probably not performance enhancing.
The myostatin mutation is interesting. I worked on this target a few years ago. It is interesting to note natural human mutants who went into bodybuilding. The mutation was first noted in bulls and whippets.
Injecting your child is just unethical.